Michail Kokkorakis
Michail Kokkorakis
MD-PhD candidate
MD-PhD candidate
Evidence-Informed Cardiometabolic Medicine 📈
Evidence-Informed Cardiometabolic Medicine 📈
Steatotic Liver Disease
Steatotic liver disease, including metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis, is the most prevalent chronic liver condition, affecting more than one-fourth of the global population. My research focuses on the pathophysiology, diagnosis, and management of steatitic liver disease according to the latest advancements in the guidelines and clinical trials.
Steatotic Liver Disease
Steatotic liver disease, including metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis, is the most prevalent chronic liver condition, affecting more than one-fourth of the global population. My research focuses on the pathophysiology, diagnosis, and management of steatitic liver disease according to the latest advancements in the guidelines and clinical trials.
Steatotic Liver Disease
Steatotic liver disease, including metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis, is the most prevalent chronic liver condition, affecting more than one-fourth of the global population. My research focuses on the pathophysiology, diagnosis, and management of steatitic liver disease according to the latest advancements in the guidelines and clinical trials.
Obesity
Obesity is considered the epidemic of the 21st century. So far, only two effective and some suboptimal drugs have been available in the clinician’s therapeutic armamentarium. However, emerging alternatives of novel agents and combination schemes are populating obesity’s therapeutic pipeline. My research focuses on emerging pharmacotherapies undergoing or having completed phase 2 and phase 3 clinical trials ultimately fostering personalized care.
Obesity
Obesity is considered the epidemic of the 21st century. So far, only two effective and some suboptimal drugs have been available in the clinician’s therapeutic armamentarium. However, emerging alternatives of novel agents and combination schemes are populating obesity’s therapeutic pipeline. My research focuses on emerging pharmacotherapies undergoing or having completed phase 2 and phase 3 clinical trials ultimately fostering personalized care.
Data Science
My research focuses on multimodal AI/ML models to stratify risk for prevalent and incident cardiometabolic diseases. Utilizing simple and complex data (i.e., imaging and omics) my algorithms meet clinical significance and are non-inferior or even better to the currently available non-invasive tools.
Data Science
My research focuses on multimodal AI/ML models to stratify risk for prevalent and incident cardiometabolic diseases. Utilizing simple and complex data (i.e., imaging and omics) my algorithms meet clinical significance and are non-inferior or even better to the currently available non-invasive tools.
Obesity
Obesity is considered the epidemic of the 21st century. So far, only two effective and some suboptimal drugs have been available in the clinician’s therapeutic armamentarium. However, emerging alternatives of novel agents and combination schemes are populating obesity’s therapeutic pipeline. My research focuses on emerging pharmacotherapies undergoing or having completed phase 2 and phase 3 clinical trials ultimately fostering personalized care.
Data Science
My research focuses on multimodal AI/ML models to stratify risk for prevalent and incident cardiometabolic diseases. Utilizing simple and complex data (i.e., imaging and omics) my algorithms meet clinical significance and are non-inferior or even better to the currently available non-invasive tools.
Steatotic Liver Disease
Steatotic liver disease, including metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis, is the most prevalent chronic liver condition, affecting more than one-fourth of the global population. My research focuses on the pathophysiology, diagnosis, and management of steatitic liver disease according to the latest advancements in the guidelines and clinical trials.
Steatotic Liver Disease
Steatotic liver disease, including metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis, is the most prevalent chronic liver condition, affecting more than one-fourth of the global population. My research focuses on the pathophysiology, diagnosis, and management of steatitic liver disease according to the latest advancements in the guidelines and clinical trials.
Obesity
Obesity is considered the epidemic of the 21st century. So far, only two effective and some suboptimal drugs have been available in the clinician’s therapeutic armamentarium. However, emerging alternatives of novel agents and combination schemes are populating obesity’s therapeutic pipeline. My research focuses on emerging pharmacotherapies undergoing or having completed phase 2 and phase 3 clinical trials ultimately fostering personalized care.
Data Science
My research focuses on multimodal AI/ML models to stratify risk for prevalent and incident cardiometabolic diseases. Utilizing simple and complex data (i.e., imaging and omics) my algorithms meet clinical significance and are non-inferior or even better to the currently available non-invasive tools.
Obesity
Obesity is considered the epidemic of the 21st century. So far, only two effective and some suboptimal drugs have been available in the clinician’s therapeutic armamentarium. However, emerging alternatives of novel agents and combination schemes are populating obesity’s therapeutic pipeline. My research focuses on emerging pharmacotherapies undergoing or having completed phase 2 and phase 3 clinical trials ultimately fostering personalized care.
Data Science
My research focuses on multimodal AI/ML models to stratify risk for prevalent and incident cardiometabolic diseases. Utilizing simple and complex data (i.e., imaging and omics) my algorithms meet clinical significance and are non-inferior or even better to the currently available non-invasive tools.
Experience 🏥
Experience 🏥
Senior Graduate Medical Intern
Senior Graduate Medical Intern
Senior Graduate Medical Intern
Medisch Spectrum Twente
Medisch Spectrum Twente
May 2024 – Present
May 2024 – Present
Doctoral Researcher
Doctoral Researcher
Doctoral Researcher
Harvard Medical School
Harvard Medical School
Oct 2022 – Present
Oct 2022 – Present
Research Affiliate
Research Affiliate
Research Affiliate
Leiden University Medical Center
Leiden University Medical Center
Feb 2024 – Present
Feb 2024 – Present
Doctoral Researcher
Doctoral Researcher
Doctoral Researcher
University Medical Center Groningen
University Medical Center Groningen
Sep 2022 – Present
Sep 2022 – Present
Junior Graduate Medical Intern
Junior Graduate Medical Intern
Junior Graduate Medical Intern
University Medical Center Groningen
University Medical Center Groningen
Apr 2023 – Apr 2024
Apr 2023 – Apr 2024
Academic Tutor
Academic Tutor
Academic Tutor
University Medical Center Groningen
University Medical Center Groningen
Sep 2022 – Sep 2024
Sep 2022 – Sep 2024
Visiting Scholar
Visiting Scholar
Visiting Scholar
University of Pennsylvania
University of Pennsylvania
Apr 2022 – Sep 2022
Apr 2022 – Sep 2022
Member of the University Council
Member of the University Council
Member of the University Council
University of Groningen
University of Groningen
Sep 2021 – Sep 2022
Sep 2021 – Sep 2022
Education 📚
Education 📚
Doctor of Philosophy (PhD)
Doctor of Philosophy (PhD)
Doctor of Philosophy (PhD)
University of Groningen
University of Groningen
Dec 2023 – Present
Dec 2023 – Present
Doctor of Medicine (MD)
Doctor of Medicine (MD)
Doctor of Medicine (MD)
University of Groningen
University of Groningen
Sep 2022 – Present
Sep 2022 – Present
Bachelor of Science (BSc) in Medicine
Bachelor of Science (BSc) in Medicine
Bachelor of Science (BSc) in Medicine
University of Groningen
University of Groningen
Sep 2019 – Jul 2022
Sep 2019 – Jul 2022
Recent Publications 🖊️
Recent Publications 🖊️
GDF-15 improves the predictive capacity of steatotic liver disease non-invasive tests for incident morbidity and mortality risk for cardio-renal-metabolic diseases and malignancies
Metabolism
(Online ahead of print)
Emerging Pharmacotherapies for Obesity: A Systematic Review
Pharmacological Reviews
(Online ahead of print)
Steatotic Liver Disease: Pathophysiology and Emerging Pharmacotherapies
Pharmacological Reviews
(May 2024)
Resmetirom, the first approved drug for the management of metabolic dysfunction-associated steatohepatitis: trials, opportunities, and challenges
Resmetirom, the first approved drug for the management of metabolic dysfunction-associated steatohepatitis: trials, opportunities, and challenges
Resmetirom, the first approved drug for the management of metabolic dysfunction-associated steatohepatitis: trials, opportunities, and challenges
Metabolism
(March 2024)
Effective questionnaire-based prediction models for type 2 diabetes across several ethnicities: a model development and validation study
EClinicalMedicine
(September 2023)
Honors & Awards 🏆
GUF-100 Prize Finalist
Distinction received for belonging to the top 3 out of >4,200 students of the Faculty of Medical Sciences and for the nomination as a finalist for the GUF-100 Prize of the University of Groningen based on academic, research, and societal achievements.
MD-PhD Scholarship
Admitted to the highly selective Doctorate of Medicine and of Philosophy (MD-PhD) track, fully funded by a scholarship of €100K from the University Medical Center Groningen.
Human Space Physiology Training
1 of 30 students selected from top European universities to participate in a fully funded, highly selective training program of the Space Medicine Team at the European Space Agency Academy’s Training & Learning Facility, ESEC-Galaxia, Belgium. Distinction received upon completion based on outstanding performance (Grade: A).
Junior Scientific Masterclass
Among the top 10% of bachelor medical graduates at the University of Groningen, graduating with Honors and excelling in the innovative scientific training program (Junior Scientific Masterclass).
ADF Lab Fund
Received funding from the Koumenis Lab, Perelman School of Medicine, University of Pennsylvania, to cover living expenses during my research internship, totaling $2,900.
UMCG Grant
Received funding from the University Medical Center Groningen to cover part of my travel expenses for my research internship at the Perelman School of Medicine, University of Pennsylvania, totaling €250.
GUF-100 Prize Finalist
Distinction received for belonging to the top 3 out of >4,200 students of the Faculty of Medical Sciences and for the nomination as a finalist for the GUF-100 Prize of the University of Groningen based on academic, research, and societal achievements.
MD-PhD Scholarship
Admitted to the highly selective Doctorate of Medicine and of Philosophy (MD-PhD) track, fully funded by a scholarship of €100K from the University Medical Center Groningen.
Human Space Physiology Training
1 of 30 students selected from top European universities to participate in a fully funded, highly selective training program of the Space Medicine Team at the European Space Agency Academy’s Training & Learning Facility, ESEC-Galaxia, Belgium. Distinction received upon completion based on outstanding performance (Grade: A).
Junior Scientific Masterclass
Among the top 10% of bachelor medical graduates at the University of Groningen, graduating with Honors and excelling in the innovative scientific training program (Junior Scientific Masterclass).
ADF Lab Fund
Received funding from the Koumenis Lab, Perelman School of Medicine, University of Pennsylvania, to cover living expenses during my research internship, totaling $2,900.
UMCG Grant
Received funding from the University Medical Center Groningen to cover part of my travel expenses for my research internship at the Perelman School of Medicine, University of Pennsylvania, totaling €250.
GUF-100 Prize Finalist
Distinction received for belonging to the top 3 out of >4,200 students of the Faculty of Medical Sciences and for the nomination as a finalist for the GUF-100 Prize of the University of Groningen based on academic, research, and societal achievements.
MD-PhD Scholarship
Admitted to the highly selective Doctorate of Medicine and of Philosophy (MD-PhD) track, fully funded by a scholarship of €100K from the University Medical Center Groningen.
Human Space Physiology Training
1 of 30 students selected from top European universities to participate in a fully funded, highly selective training program of the Space Medicine Team at the European Space Agency Academy’s Training & Learning Facility, ESEC-Galaxia, Belgium. Distinction received upon completion based on outstanding performance (Grade: A).
Junior Scientific Masterclass
Among the top 10% of bachelor medical graduates at the University of Groningen, graduating with Honors and excelling in the innovative scientific training program (Junior Scientific Masterclass).
ADF Lab Fund
Received funding from the Koumenis Lab, Perelman School of Medicine, University of Pennsylvania, to cover living expenses during my research internship, totaling $2,900.
UMCG Grant
Received funding from the University Medical Center Groningen to cover part of my travel expenses for my research internship at the Perelman School of Medicine, University of Pennsylvania, totaling €250.
GUF-100 Prize Finalist
Distinction received for belonging to the top 3 out of >4,200 students of the Faculty of Medical Sciences and for the nomination as a finalist for the GUF-100 Prize of the University of Groningen based on academic, research, and societal achievements.
MD-PhD Scholarship
Admitted to the highly selective Doctorate of Medicine and of Philosophy (MD-PhD) track, fully funded by a scholarship of €100K from the University Medical Center Groningen.
Human Space Physiology Training
1 of 30 students selected from top European universities to participate in a fully funded, highly selective training program of the Space Medicine Team at the European Space Agency Academy’s Training & Learning Facility, ESEC-Galaxia, Belgium. Distinction received upon completion based on outstanding performance (Grade: A).
Junior Scientific Masterclass
Among the top 10% of bachelor medical graduates at the University of Groningen, graduating with Honors and excelling in the innovative scientific training program (Junior Scientific Masterclass).
ADF Lab Fund
Received funding from the Koumenis Lab, Perelman School of Medicine, University of Pennsylvania, to cover living expenses during my research internship, totaling $2,900.
UMCG Grant
Received funding from the University Medical Center Groningen to cover part of my travel expenses for my research internship at the Perelman School of Medicine, University of Pennsylvania, totaling €250.
Honors & Awards 🏆
GUF-100 Prize Finalist
Distinction received for belonging to the top 3 out of >4,200 students of the Faculty of Medical Sciences and for the nomination as a finalist for the GUF-100 Prize of the University of Groningen based on academic, research, and societal achievements.
MD-PhD Scholarship
Admitted to the highly selective Doctorate of Medicine and of Philosophy (MD-PhD) track, fully funded by a scholarship of €100K from the University Medical Center Groningen.
Human Space Physiology Training
1 of 30 students selected from top European universities to participate in a fully funded, highly selective training program of the Space Medicine Team at the European Space Agency Academy’s Training & Learning Facility, ESEC-Galaxia, Belgium. Distinction received upon completion based on outstanding performance (Grade: A).
Junior Scientific Masterclass
Among the top 10% of bachelor medical graduates at the University of Groningen, graduating with Honors and excelling in the innovative scientific training program (Junior Scientific Masterclass).
ADF Lab Fund
Received funding from the Koumenis Lab, Perelman School of Medicine, University of Pennsylvania, to cover living expenses during my research internship, totaling $2,900.
UMCG Grant
Received funding from the University Medical Center Groningen to cover part of my travel expenses for my research internship at the Perelman School of Medicine, University of Pennsylvania, totaling €250.
GUF-100 Prize Finalist
Distinction received for belonging to the top 3 out of >4,200 students of the Faculty of Medical Sciences and for the nomination as a finalist for the GUF-100 Prize of the University of Groningen based on academic, research, and societal achievements.
MD-PhD Scholarship
Admitted to the highly selective Doctorate of Medicine and of Philosophy (MD-PhD) track, fully funded by a scholarship of €100K from the University Medical Center Groningen.
Human Space Physiology Training
1 of 30 students selected from top European universities to participate in a fully funded, highly selective training program of the Space Medicine Team at the European Space Agency Academy’s Training & Learning Facility, ESEC-Galaxia, Belgium. Distinction received upon completion based on outstanding performance (Grade: A).
Junior Scientific Masterclass
Among the top 10% of bachelor medical graduates at the University of Groningen, graduating with Honors and excelling in the innovative scientific training program (Junior Scientific Masterclass).
ADF Lab Fund
Received funding from the Koumenis Lab, Perelman School of Medicine, University of Pennsylvania, to cover living expenses during my research internship, totaling $2,900.
UMCG Grant
Received funding from the University Medical Center Groningen to cover part of my travel expenses for my research internship at the Perelman School of Medicine, University of Pennsylvania, totaling €250.
GUF-100 Prize Finalist
Distinction received for belonging to the top 3 out of >4,200 students of the Faculty of Medical Sciences and for the nomination as a finalist for the GUF-100 Prize of the University of Groningen based on academic, research, and societal achievements.
MD-PhD Scholarship
Admitted to the highly selective Doctorate of Medicine and of Philosophy (MD-PhD) track, fully funded by a scholarship of €100K from the University Medical Center Groningen.
Human Space Physiology Training
1 of 30 students selected from top European universities to participate in a fully funded, highly selective training program of the Space Medicine Team at the European Space Agency Academy’s Training & Learning Facility, ESEC-Galaxia, Belgium. Distinction received upon completion based on outstanding performance (Grade: A).
Junior Scientific Masterclass
Among the top 10% of bachelor medical graduates at the University of Groningen, graduating with Honors and excelling in the innovative scientific training program (Junior Scientific Masterclass).
ADF Lab Fund
Received funding from the Koumenis Lab, Perelman School of Medicine, University of Pennsylvania, to cover living expenses during my research internship, totaling $2,900.
UMCG Grant
Received funding from the University Medical Center Groningen to cover part of my travel expenses for my research internship at the Perelman School of Medicine, University of Pennsylvania, totaling €250.
GUF-100 Prize Finalist
Distinction received for belonging to the top 3 out of >4,200 students of the Faculty of Medical Sciences and for the nomination as a finalist for the GUF-100 Prize of the University of Groningen based on academic, research, and societal achievements.
MD-PhD Scholarship
Admitted to the highly selective Doctorate of Medicine and of Philosophy (MD-PhD) track, fully funded by a scholarship of €100K from the University Medical Center Groningen.
Human Space Physiology Training
1 of 30 students selected from top European universities to participate in a fully funded, highly selective training program of the Space Medicine Team at the European Space Agency Academy’s Training & Learning Facility, ESEC-Galaxia, Belgium. Distinction received upon completion based on outstanding performance (Grade: A).
Junior Scientific Masterclass
Among the top 10% of bachelor medical graduates at the University of Groningen, graduating with Honors and excelling in the innovative scientific training program (Junior Scientific Masterclass).
ADF Lab Fund
Received funding from the Koumenis Lab, Perelman School of Medicine, University of Pennsylvania, to cover living expenses during my research internship, totaling $2,900.
UMCG Grant
Received funding from the University Medical Center Groningen to cover part of my travel expenses for my research internship at the Perelman School of Medicine, University of Pennsylvania, totaling €250.
Podcast 📻
Podcast 📻
Tune in to our Podcast!
Tune in to our Podcast!
Tune in to our Podcast!
Michail Kokkorakis